一、个人基本情况: 女，硕士，赣南师范大学化学与材料让球盘 副教授，硕士研究生导师。

   二、主要研究方向：有机化学、药物化学

本人主要从事合成药物化学研究。

联系方式：Email: [email protected]

   三、主要学术成果：

近年来先后主持/完成国家自然科学基金2项，江西省自然科学基金面上项目1项和江西省学位与研究生教育教学改革重点项目1项。在Org. Lett., Eur. J. Med. Chem., Org. Chem. Front., J. Org. Chem.等高水平学术期刊发表SCI论文20余篇，授权国家发明专利10余项。

科研项目：

[1] 国家自然科学基金地区项目，22167002、2022/01-2025/12、已结题、主持。

[2] 国家自然科学基金青年项目（青C），21602031、2017/01-2019/12、已结题、主持。

[3] 江西省自然科学基金面上项目，20242BAB25549、2024/06-2026/06、在研、主持。

[4] 江西省学位与研究生教育教学改革重点项目，JXYJG-2023-161、2023/01-2026/12、在研、主持。

近五年部分代表性成果总结如下：

[1] Lin, Y.; Chen, P.; Zhu, X.; Zhu, S.; Cheng, N.; Guo, W.; Zheng, L.* Research progress on single-atom skeletal editing of cyclic organic compounds: reactions and mechanisms. Org. Chem. Front. 2026, Doi: 10.1039/D6QO00387G.

[2] Hua, X.; Cheng, N.; Zhu, S.; Wang, Y.; Wu, Y.; Guo, W.; Zheng, L.* Recent Advances in the Synthesis of Nitrogen-Containing Heterocycles from ο-Aminobenzamides: Reactions and Mechanism. Adv. Synth. Catal. 2026, 368, e70471.  

[3] Zheng, L.*; Zhong, Y.; Li, Y.; Chen, P.; Cheng, N.; Hua, X.; Ouyang, L.; Luo, N.; Shen, J.; Li, Y.; Guo, W.* Discovery and Biological Evaluation of Novel N-Aryl-N’-methylbenzodrazides Against Schistosoma japonicum In Vitro and In Vivo. Microbiol. Spectr. 2026, 14, e01932-25.  

[4] Li, Y.; Deng, L.; Hua, X.; Zhong, Y.; Chen, P.; Shen, J.; Ouyang, L.; Zheng, L.*; Guo, W.* Design, Synthesis and Preliminary Structure-Activity Relationship of 2-Iminothiazolidine-4-one Derivatives Against Schistosoma japonicum In Vitro and In Vivo. Eur. J. Med. Chem. 2025, 290, 117567.

[5] Wang, Y.; Yang, X.; Zhang, Z.; Hua, X.; Lin, Y.; Chen, P.; Zhu, X.; Guo, W.; Zheng, L.* Easy Access to α,β-Diamino-Substituted Cyclopentenaminones through Copper-Catalyzed Double Amination of Unactivated Cyclic Ketones. J. Org. Chem. 2025, 90, 7406-7416. 

[6] Zheng, L.*; Yang, B.; Zhu, X.; Zhang, Z.; Hua, X.; Chen, P.; Lin, Y.; Guo, W.* TEMPO Oxidative [3 + 2] Cycloaddition of N-Substituted Acrylamides and α-Diazoacetates: Access to Carbamoyl-Substituted Pyrazole-5-carboxylates. J. Org. Chem. 2025, 90, 9903-9917.

[7] Wang, Y.; Hua, X.; Li, Y.; Zhang, Z.; Lin, Y.; Guo, W.; Zheng, L.* Controllable Molecular Editing of 2AminoNsubstituted Benzamides: Site-selective Synthesis of 6Selenylated NSubstituted 1,2,3-Benzotriazine-4(3H)ones. Org. Lett. 2025, 27, 1441-1446.

[8] Wang, Y.; Yang, B.; Wang, B.; Li, Y.; Zhang, Z.; Wang, Y.; Guo, W.; Tan, Z.; Zheng, L.* Palladium-Copper-Catalyzed Oxidative Intermolecular [2 + 2 + 2] Coupling-Annulation: Regioselective Synthesis of Multiaryl-Substituted Benzenes. J. Org. Chem. 2024, 89, 4579-4594.

[9] Zhuo, X.; Zheng, L.*; Liu, Y.; Wang, Y.; Zou, X.; Zhong, Y. Guo, W. Visible Light-Enhanced [3 + 2] Cycloaddition of N,N-Disubstituted Hydrazines with Organo-Cyanamides: Access to Polysubstituted 1,2,4-Triazol-3-amines. J. Org. Chem. 2024, 89, 994-1009.

[10] Zheng, L.*; Zou, X.; Yang, X.; Deng, L.; Guo, W.* Visible-Light-Catalyzed Formal [3 + 2] Annulation-Aromatization of Amidines with Isoquinolinium N-Ylides: Access to Imidazo[2,1-a]isoquinolines. Adv. Synth. Catal. 2023, 365, 3629-3636. 

[11] Zheng, L.; Deng, L.; Zhong, Y.; Wang, Y.; Guo, W.*; Fan, X.* Molluscicides against the snail-intermediate host of Schistosoma: a review. Parasitol. Res. 2021, 120, 3355-3393.